Gene Expression Patterns in Human Liver Cancers
نویسندگان
چکیده
منابع مشابه
Gene expression patterns in human liver cancers.
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA microarrays to characterize patterns of gene expression in HCC, we found consistent differences between the expression patterns in HCC compared with those seen in nontumor liver tissues. The expression patterns in HCC were also readily distinguished from those associated with tumors metastatic to liver. The global ...
متن کاملVariation in gene expression patterns in human gastric cancers.
Gastric cancer is the world's second most common cause of cancer death. We analyzed gene expression patterns in 90 primary gastric cancers, 14 metastatic gastric cancers, and 22 nonneoplastic gastric tissues, using cDNA microarrays representing approximately 30,300 genes. Gastric cancers were distinguished from nonneoplastic gastric tissues by characteristic differences in their gene expression...
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At present, a full understanding of the mechanisms by which colorectal cancer (CRC) distant metastases form is still beyond our reach because of the intricate regulation of gene expression. MicroRNAs (miRNAs) are shown to be involved in various human diseases including cancers through negative regulation of target gene expression at the post-transcriptional level. However, there are only a few ...
متن کاملDistinctive gene expression patterns in human mammary epithelial cells and breast cancers.
cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of coexpressed genes identified through manipulations of mammary epithelial cells in vitro also showed consistent patterns of variation in expression among breast tumor samples. By using immunohistochemist...
متن کامل[Identification of gene expression patterns in superficial and invasive human bladder cancers].
OBJECTIVE To study the difference of gene expression patterns in invasive and superficial human bladder cancers. METHODS cDNA microarray was used to detect the RNA in 12 samples of invasive and superficial human bladder cancers and 6 samples of normal bladder tissues as control group obtained during operation. Then, the scanogram was analyzed by applying the image processing software GenePix ...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2002
ISSN: 1059-1524
DOI: 10.1091/mbc.02-02-0023.